myGwork - LGBTQ+ Business Community · 3 days ago

Senior Research Scientist- Hematopoietic Stem Cell Biology

Boston, MA

Full-time

Onsite

Senior Level

2+ years exp

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Responsibilities

Drive the preclinical pipeline development of programs based on manipulation of blood stem cells (e.g. hematopoietic stem cells) for diseases of the blood and immune system.

Contribute to preclinical pipeline programs all the way from discovery to preclinical proof-of-concept and IND-enabling studies.

Design, execute, and interpret data for experiments in human primary cells, humanized mice and larger animals.

Communicate scientific data and draw appropriate conclusions effectively, internally and externally.

Contribute to high quality departmental documents for regulatory submissions, manuscripts, abstracts and publications.

Effectively collaborate with a fully integrated team to facilitate the success of projects, as well as, assist others outside of own project with troubleshooting and methods development.

Build and maintain strong collaborative partnerships with other R&D disciplines to advance Vertex programs through discovery and development.

Develop strategies to ensure effective achievement of broader company scientific objectives

Qualification

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Molecular Cell BiologyDevelopmental BiologyStem Cell BiologyHematopoietic Stem Cell BiologyPreclinical ModelsAssay DevelopmentExperimental DesignHuman Stem Cell ModelsTarget EvaluationIndustry ExperienceProject ManagementScientific KnowledgeProblem-SolvingEffective CommunicationTeamwork

Required

Ph.D. (or equivalent degree) in molecular and cell biology, developmental biology, stem cell biology, or related disciplines and 2-5 years of relevant post-doctoral employment experience

Masters Degree (or equivalent degree) in molecular and cell biology, developmental biology, stem cell biology, or related disciplines and 5+ years of relevant employment experience

Bachelors Degree (or equivalent degree) in molecular and cell biology, developmental biology, stem cell biology, or related disciplines and 8+ years of relevant employment experience

Expertise in the field of hematopoietic stem cell biology and deep understanding of preclinical models of hematopoietic stem cell biology

Direct industry experience working on teams responsible for developing assays using primary cells

Ability to design and execute more challenging experiments including the development of human stem cell models and assays to evaluate targets and lead molecules for Vertex diseases

Demonstrates astute understanding of how to deploy own talents most effectively

Maintains a broad knowledge of relevant science beyond own discrete field(s)

Communicates effectively in verbal presentations and in writing technical reports

Demonstrates ability to solve problems to attain crucial project goals