Sanofi · 2 days ago
Senior Scientist
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Health CareLife Science
Insider Connection @Sanofi
Responsibilities
Performing structure-based protein engineering and optimizing antigen display on various platforms using computational tools like Schrödinger, MOE, and Rosetta.
Designing novel antigens with conformational B cell epitopes, T cell epitopes, and minimal off-target immunogenicity.
Leading the investigation and development of next-generation methods for computational biology.
Performing cryo-EM sample preparation, data collection, and model building for viral and bacterial antigen/antibody complexes.
Networking internally and externally, participating in relevant project teams, and maintaining communication with various company areas.
Qualification
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Required
PhD in Computational Biology, Biophysics, Structural Biology, or closely-related discipline.
Experience with Schrödinger, MOE or Rosetta is required.
Experience with cryo-EM sample preparation and grid clipping is required.
Experience with cryo-EM machines (Glacios and Krios) and familiarity with cryo-EM data collection software (SerialEM and EPU) is required.
Experience with cryo-EM data processing (CryoSPARC) and model building (Coot and Phenix, Isolde) is required.
Ability to independently design, plan and execute scientific studies, including operation and maintenance of relevant instruments and troubleshooting are required.
Advanced skill in structural viewing program such as Pymol and ChimeraX is required.
Experience with viral fusion protein and antibody biology is required.
Preferred
Experience with Alphafold 3 and molecular dynamics is preferred.
Benefits
High-quality healthcare
Prevention and wellness programs
At least 14 weeks' gender-neutral parental leave
Company
Sanofi
Sanofi is a healthcare company that provides treatments and the protection of life-saving vaccines.
H1B Sponsorship
Sanofi has a track record of offering H1B sponsorships. Please note that this does not
guarantee sponsorship for this specific role. Below presents additional info for your
reference. (Data Powered by US Department of Labor)
Distribution of Different Job Fields Receiving Sponsorship
Trends of Total Sponsorships
2023 (30)
2022 (95)
2021 (44)
2020 (45)
Funding
Current Stage
Public CompanyTotal Funding
$639.02MKey Investors
Blackstone Life SciencesEvotec
2022-03-15Post Ipo Equity· $329.02M
2014-12-02Post Ipo Equity· $310M
2002-07-12IPO· nyse:SNY
Leadership Team
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